• Grand Fiesta Americana Coral Beach Cancún Blvd. Kukulcan km. 9.5, Punta Cancun, Zona Hotelera, 77500 Cancún, Q.R.
  • +52 1 81 1185 0158
  +52 1 81 1185 0158
Program
Thursday, December 4: Meet and greet in the evening
Friday, December 5: Half day scientific meeting followed by an evening reception/dinner Optional afternoon Master Class: Drug Induced Liver Injury and Drug Safety for Clinicians and Clinical Researchers
Saturday, December 6: Half day scientific meeting followed by a formal close-out dinner
Sunday, December 7: Departures

On DECEMBER 5, 2025
7:30 - 8:15 a.m. Breakfast
 
8:15 - 11:00 a.m.
Session 1  Moderators: Drs. Chalasani & Lewis
8:15 - 8:30 a.m
Welcome Address - Drs. Chalasani and Lewis
8:30 - 10:30 a.m
What's New in 2025
8:30 - 9:10 a.m ● Published (peer reviewed) - 40 min. Impactful DILI publications relevant to hepatic safety, Dr. Chalasani
9:10 - 9:50 a.m ● Unpublished (press releases) - 40 min. Updates from ongoing drug development programs related to hepatic safety, Dr. Vuppalanchi
9:50 - 10:10 a.m ● Regulatory updates - 40 min. Updates from ongoing drug development programs related to hepatic safety, Dr. Hayashi
10:10 - 10:30 a.m ● Industry updates - 20 min. Building hepatic safety dossiers for NDA submission, Dr. Regev
10:30 - 10:45 a.m Q&A
 
10:45 - 11:00 a.m. Break
 
11:00 a.m. – 13:30 p.m.
Session 2 - Chair, Dr. Lewis
11:00 a.m. - 12:00 p.m.
Case-based Panel Discussion: Drs. Chalasani, Lewis, Regev, Hayashi, Garcia Audience response system used
11:00 a.m. - 11:20 a.m. ● Case 1 - 20 min - led by Dr. Lewis
11:20 a.m. - 11:40 a.m. ● Case 2 - 20 min - led by Dr. Ghabril
11:40 a.m. - 12:00 p.m. ● Case 3 - 20 min - led by Dr. Vuppalanchi
12:00 p.m. - 12:25 p.m. ABC of Data Safety Monitoring Board (DSMB) - Dr. Rockhold to review charter, chair responsibilities, and review of TFLs
12:30 p.m. - 12:55 p.m. Real-world Evidence for Safety and Efficacy - Dr. Rockhold
13:00 p.m. - 13:25 p.m. HAC: From Charter to Safety Summary - Dr. Lewis to review the inner workings of the Hepatic Adjudication Committee
 
13:00 – 14:00 p.m. Lunch
 
13:00- 16:30 p.m Virtual Master Class: Drug Induced Liver Injury and Liver Safety for Clinicians and Clnical Researchers (optional attendance)
18:00 p.m. - 19:00 p.m. Welcome Reception
19:00 p.m. - 21:00 p.m. Dinner

On DECEMBER 6 , 2025
7:00 - 8:30 a.m. Business Meeting (members only, closed session)
8:15 - 9:00 a.m.
Breakfast
9:00 - 11:00 a.m.
Session 3 - Chairs, Drs. Dara and Ghabril
  Overviews: Things You Must Know A series of focused talks on DILI across therapeutic areas
9:00 - 9:20 a.m
● ICI Liver Injury - 20 min. Dr. Ahmad
9:25 - 9:45 a.m ● TKI Liver Injury - 20 min. Dr. Dara
9:50 - 10:10 a.m ● Chemotherapeutic Agents - 20 min. Dr. Vuppalanchi
10:15 - 10:35 a.m ● CNS Agents - 20 min. Dr. Ghabril
10:40 - 11:00 a.m ● Cardiac Drugs and Anticoagulants - 20 min. Dr. Barritt
 
11:00 - 11:30 a.m. Break
 
11:30 a.m. – 13:00 p.m.
Session 4 - Chair, Dr. Vuppalanchi
 
Other Interesting Topics: Emerging topics in hepatic safety and drug safety surveillance
11:00 a.m. - 11:20 a.m. ● Commonly Used Drugs and DILI Risk Categories (LiverTox) -20 min. Dr. DeLemos
11:25 a.m. - 11:45 a.m. ● Cardio-Oncology - 20 min. Dr. Kovacs
11:50 a.m. - 12:10 p.m. ● Post-marketing Safety Surveillance - 20 min. Dr. Regev
12:10 p.m. - 13:00 p.m. Imagining an AI-based Future in Liver Safety
A forward looking session exploring the role of artificial intelligence in improving liver safety monitoring, prediction, and evaluation
 
13:00 – 14:00 p.m. Lunch
 
18:00 p.m. - 19:00 p.m. Reception
19:00 p.m. - 21:00 p.m. Dinner